Late toxicity and biochemical recurrence after external-beam radiotherapy combined with permanent-source prostate brachytherapy

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Late toxicity and biochemical recurrence after external-beam radiotherapy combined with permanent-source prostate brachytherapy: analysis of Radiation Therapy Oncology Group study 0019.

BACKGROUND The combination of external-beam radiotherapy and brachytherapy is used commonly to treat men with prostate cancer. In this analysis, the authors examined the rate of biochemical recurrence (BR) and late grade > or =3 genitourinary (GU) and gastrointestinal (GI) toxicity after treatment with external-beam radiotherapy and brachytherapy in a multiinstitutional, cooperative group setti...

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Combining external beam radiotherapy with prostate brachytherapy: issues and rationale.

a he optimal treatment for clinically localized prostate cancer remains controversial. For paients with low-risk prostate cancer (Stage T1c2a, Gleason score less than 7, prostate-specific ntigen [PSA] of 10.0 ng/mL), monotherapy with adical prostatectomy, three-dimensional conforal radiotherapy (3D-CRT), intensity-modulated T, or prostate brachytherapy results in similar iochemical relapse-free...

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Combination therapy-permanent interstitial brachytherapy and external beam radiotherapy for patients with localized prostate cancer.

BACKGROUND Combination of permanent interstitial brachytherapy based on radioactive iodine with external beam radiotherapy is an alternative to other treatment modalities, such as radical prostatectomy or external beam radiotherapy alone in patients with intermediate-risk localized prostate cancer. In this article we report our experience with this combination modality. METHODS Among patients...

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Late genitourinary and gastrointestinal toxicity after magnetic resonance image-guided prostate brachytherapy with or without neoadjuvant external beam radiation therapy.

BACKGROUND This study was designed to estimate the rates of late genitourinary (GU) and rectal toxicity after magnetic resonance image (MRI)-guided prostate brachytherapy exclusively or in conjunction with external beam radiation therapy (EBRT). METHODS Between November 1997 and April 2002, 201 patients with category T1C prostate carcinoma (according to the 2002 American Joint Committee on Ca...

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Long-term biochemical results after high-dose-rate intensity modulated brachytherapy with external beam radiotherapy for high risk prostate cancer

BACKGROUND Biochemical control from series in which radical prostatectomy is performed for patients with unfavorable prostate cancer and/or low dose external beam radiation therapy are given remains suboptimal.The treatment regimen of HDR brachytherapy and external beam radiotherapy is a safe and very effective treatment for patients with high risk localized prostate cancer with excellent bioch...

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ژورنال

عنوان ژورنال: Cancer

سال: 2007

ISSN: 0008-543X,1097-0142

DOI: 10.1002/cncr.22560